Mind the gap: Are we missing something in how we determine optimal intervals between Covid-19 vaccine doses?

The controversy around intervals between Covid-19 doses has pitted the desire to expand access to a first dose as broadly and quickly as possible against available efficacy data. Unfortunately, in focusing on these critical issues, we have overlooked another key consideration.

First, some background. At the end of 2020, the UK shifted its Covid-19 immunization policy to prioritize immunizing as many at risk-individuals as possible with a first dose…